| R | Player | Match | Runs | 4s |
|---|---|---|---|---|
| 1 |  Dane Van Niekerk WP-W | 5 | 214 | 28 |
| 2 |  Nicole de Klerk DOL-W | 5 | 169 | 21 |
| 3 |  Faye Tunnicliffe WP-W | 4 | 152 | 20 |
| 4 |  Nadine Moodley SWD-W | 5 | 114 | 19 |
| 5 |  Verunissa Reddy KN-W | 5 | 112 | 19 |
| 6 |  Lara Goodall WP-W | 4 | 108 | 16 |
| 7 |  Alexandra Candler DOL-W | 6 | 158 | 16 |
| 8 |  Nonkhululeko Thabethe LIO-W | 4 | 144 | 15 |
| 9 |  Amogelang Maphangulaa TIT-W | 4 | 99 | 15 |
| 10 |  Babette de Leede WP-W | 5 | 94 | 14 |
| 11 |  Kirstie Thomson LIO-W | 4 | 78 | 12 |
| 12 |  Jana Nell SWD-W | 5 | 126 | 12 |
| 13 |  Nondumiso Shangase DOL-W | 5 | 83 | 11 |
| 14 |  Tazmin Brits LIO-W | 2 | 95 | 10 |
| 15 |  Miane Smit KN-W | 3 | 73 | 10 |