| R | Player | Match | Runs | 4s |
|---|---|---|---|---|
| 1 |  Eve Jones THU | 15 | 556 | 71 |
| 2 |  Grace Scrivens SUN | 16 | 553 | 69 |
| 3 |  Bryony Smith SES | 12 | 413 | 58 |
| 4 |  Alice Davidson-Richards SES | 16 | 650 | 56 |
| 5 |  Hollie Armitage NOD | 12 | 435 | 51 |
| 6 |  Cordelia Griffith SUN | 13 | 420 | 50 |
| 7 |  Lauren Winfield-Hill NOD | 14 | 361 | 50 |
| 8 |  Seren Smale THU | 13 | 515 | 49 |
| 9 |  Georgia Elwiss SV | 12 | 488 | 48 |
| 10 |  Fran Wilson WS | 14 | 500 | 47 |
| 11 |  Natasha Wraith WS | 14 | 428 | 45 |
| 12 |  Ella McCaughan SV | 13 | 340 | 45 |
| 13 |  Charli Knott SV | 9 | 346 | 44 |
| 14 |  Sophie Luff WS | 14 | 491 | 43 |
| 15 |  Emma Marlow NOD | 13 | 397 | 42 |