| R | Player | Match | Runs | Avg. |
|---|---|---|---|---|
| 1 |  Sophia Dunkley SES | 5 | 293 | 97.66 |
| 2 |  Georgia Elwiss SV | 12 | 488 | 69.71 |
| 3 |  Freya Kemp SV | 5 | 128 | 64.00 |
| 4 |  Heather Knight WS | 1 | 62 | 62.00 |
| 5 |  Grace Scrivens SUN | 16 | 553 | 50.27 |
| 6 |  Kira Chathli SES | 6 | 251 | 50.20 |
| 7 |  Charli Knott SV | 9 | 346 | 49.42 |
| 8 |  Tash Farrant SES | 7 | 280 | 46.66 |
| 9 |  Alice Davidson-Richards SES | 16 | 650 | 46.42 |
| 10 |  Kathryn Bryce BLA | 8 | 272 | 45.33 |
| 11 |  Hollie Armitage NOD | 12 | 435 | 43.50 |
| 12 |  Eve Jones THU | 15 | 556 | 42.76 |
| 13 |  Fran Wilson WS | 14 | 500 | 41.66 |
| 14 |  Sophie Luff WS | 14 | 491 | 40.91 |
| 15 |  Katie Mack THU | 9 | 324 | 40.50 |