| R | Player | Match | Runs | 4s |
|---|---|---|---|---|
| 1 |  Danni Wyatt SV | 6 | 273 | 43 |
| 2 |  Bryony Smith SES | 7 | 256 | 39 |
| 3 |  Maia Bouchier SV | 6 | 196 | 34 |
| 4 |  Lauren Winfield NOD | 7 | 171 | 31 |
| 5 |  Natalie Sciver-Brunt BLA | 4 | 194 | 30 |
| 6 |  Georgia Adams SV | 9 | 249 | 29 |
| 7 |  Fi Morris THU | 8 | 209 | 28 |
| 8 |  Tammy Beaumont BLA | 6 | 191 | 27 |
| 9 |  Georgie Boyce BLA | 8 | 200 | 27 |
| 10 |  Emma Lamb THU | 6 | 200 | 26 |
| 11 |  Danielle Gibson WS | 6 | 166 | 26 |
| 12 |  Fran Wilson WS | 7 | 186 | 26 |
| 13 |  Phoebe Franklin SES | 7 | 196 | 25 |
| 14 |  Amy Jones CES | 4 | 167 | 24 |
| 15 |  Cordelia Griffith SUN | 6 | 205 | 24 |