| R | Player | Match | Runs | 4s |
|---|---|---|---|---|
| 1 |  Beth Mooney PS-W | 14 | 547 | 68 |
| 2 |  Katie Mack AS-W | 17 | 513 | 62 |
| 3 |  Georgia Redmayne BH-W | 14 | 437 | 54 |
| 4 |  Elyse Villani MS-W | 12 | 439 | 53 |
| 5 |  Sophie Devine PS-W | 14 | 442 | 52 |
| 6 |  Grace Harris BH-W | 14 | 420 | 49 |
| 7 |  Smriti Mandhana ST-W | 13 | 377 | 43 |
| 8 |  Dane Van Niekerk AS-W | 17 | 356 | 43 |
| 9 |  Jemimah Rodrigues MR-W | 13 | 333 | 42 |
| 10 |  Laura Wolvaardt AS-W | 17 | 381 | 42 |
| 11 |  Mignon du Preez HB-W | 14 | 414 | 40 |
| 12 |  Ellyse Perry SS-W | 13 | 358 | 34 |
| 13 |  Harmanpreet Kaur MR-W | 13 | 406 | 33 |
| 14 |  Georgia Voll BH-W | 14 | 282 | 33 |
| 15 |  Rachel Priest HB-W | 14 | 262 | 31 |